The cancer detector developed by Japanese researchers with the sniffing sense of the mosquito is aimed to be put into practical use within 10 years.
The team produced an artificial cell membrane by placing the mosquito’s olfactory receptor that can detect “octenol”, which is found in human sweat and is considered a biomarker of liver cancer.
Developing a sensor that can detect the electric current occurring in the passage of ions between the artificial membrane, the team was able to detect the “octenol” in breath samples at half a billionth density with a lunchbox-sized prototype in 10 minutes.
The detector, which is planned to be produced at low cost in order to detect the odor-emitting substance in the breath of cancer patients, is aimed to be put into practical use within 10 years.
Published in the magazine in the USA
Mosquitoantenna has about 100 kinds of scent receptors and each one detects the specific scent-emitting substance. All these receptors are on the surface of the olfactory cells.
When scent receptors combine with special scent molecules, a hole is opened on the surface of the cell membrane to allow ions to enter the cell, thereby detecting odor.
Details of the research have been published in the Journal of Scientific Progress from the USA.